Side effects of letrozole Femara

Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. After the menopause, women don’t produce oestrogen from their ovaries.

• You should only take this drug if you have been through your menopause.
• But be sure to check with your doctor or pharmacist before taking any OTC medications.
• It can usually be relieved with mild pain relief like paracetamol or an anti-inflammatory drug such as ibuprofen.
• Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems.
• It works by decreasing the amount of estrogen produced by the body.

You must check to make sure that it is safe for you to take letrozole with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Letrozole comes as a tablet to take by mouth once a day with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

1 Adjuvant Treatment of Early Breast Cancer

As long as you have taken it for at least 5 years, then letrozole should continue to reduce the risk of breast cancer coming back for many years after you stop taking it. Letrozole is usually taken for 5 years, but may be recommended for up to 10 years depending on individual circumstances. The American Society of Clinical Oncology (ASCO) recommends that 10 years should be the maximum duration of therapy, based on their 2019 clinical practice guideline update. Two large randomized, controlled, multinational (predominantly European) trials (AR/BC2, AR/BC3) were conducted in patients with advanced breast cancer who had progressed despite antiestrogen therapy. In each study over 60% of the patients had received therapeutic antiestrogens, and about one-fifth of these patients had an objective response. The megestrol acetate controlled study was double-blind; the other study was open label.

Letrozole oral tablets brand-name versions

https://www.nationalpitbullvictimawareness.org/us-buysteroidsgroup-net/new-study-reveals-positive-effects-of-letrozol-2-5/ is used to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal). It is also used for women who have already had other cancer treatments (eg, tamoxifen). Letrozole is for use only in women who can no longer get pregnant. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of letrozole.

Letrozole Prescribing Information

The following adverse reactions have been identified during postapproval use of letrozole. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Blood clots can be harmful but are treatable so it’s important to report symptoms as soon as possible. To help keep your bones healthy you can increase your intake of calcium and vitamin D. You may also want to eat more foods that are rich in calcium, such as milk, cheese, yoghurt and cereals. For vitamin D, you can increase the amount of oily fish, mushrooms and eggs you eat.